Electrical Impedance Spectroscopy

The core technology behind Zilico’s products is electrical impedance spectroscopy (EIS).  This is a measure of the impedance (resistivity) of cells across a range of frequencies producing a spectrum showing the change of impedance with frequency.  These changes can be related to changes in the underlying nature of the biological tissue.

Biological tissues have electrical impedance, which is a function of frequency. The reason for this dependence is that tissues contain components with both resistive and charge storage (capacitive) properties, so giving rise to a complex electrical impedance. The magnitude of the impedance and the dependence of impedance on frequency are both a function of tissue composition.